09:00 - 09:15
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Introduction |
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09:15 - 10:15
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Integrative and statistical approaches to model diseases |
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09:15 - 09:30 |
› Modelling miRNA regulation in models of Huntington's disease - Lucile Mégret, Adaptation Biologique et Vieillissement |
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09:30 - 09:45 |
› Computing competing risks based on family history in genetic disease with variable age at onset - Alexandra Lefebvre, Laboratoire de Probabilité et Modèles Aléatoires |
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09:45 - 10:00 |
› Interrelations between lifestyle factors, gut microbiota characteristics, and cardiometabolic diseases in the European MetaCardis project - Karen Assman, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition |
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10:00 - 10:15 |
› How pairwise coevolutionary models capture the collective residue variability in proteins - Pierre Barrat-Charlaix, Biologie Computationnelle et Quantitative |
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10:15 - 10:45
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Coffee break |
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10:45 - 11:30
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TBA - Vincent Fromion, Unité MaIAGE, INRA Jouy-en-Josas |
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11:30 - 12:00
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DNA structures, dynamics and interactions with proteins |
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11:30 - 11:45 |
› Des noyaux et des polymères - Antony LESAGE, Laboratoire de Physique Théorique de la Matière Condensée |
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11:45 - 12:00 |
› JET2DNA: towards an accurate prediction of multiple recognition patches in protein-DNA interactions - Flavia Corsi, Sorbonne Universités, UPMC University Paris 06, CNRS, IBPS, UMR 7238, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), 75005 Paris, France, Sorbonne Universités, UPMC University Paris 06, Institut des sciences du calcul et des données, Paris, France |
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12:00 - 12:30
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Protein structures, dynamics and interactions I |
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12:00 - 12:15 |
› Proteins and their multiple interaction sites - Dequeker Chloé, Laboratoire de Biologie Computationnelle et Quantitative |
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12:15 - 12:30 |
› Structural and dynamics studies of a potassium channel and disease-associated mutants - Charline FAGNEN, Laboratoire de Biologie et de Pharmacologie Appliquée, Institut de minéralogie, de physique des matériaux et de cosmochimie |
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12:30 - 14:00
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Lunch |
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14:00 - 14:45
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Engineering small artificial RNAs - François Major, IRIC, Université de Montréal |
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14:45 - 15:45
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Protein structures, dynamics and interactions II |
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14:45 - 15:00 |
› Computation of ribbons for interactive molecular modeling - Olivier Ameline, Laboratoire Jean Perrin |
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15:00 - 15:15 |
› Gradient conjugué tronqué : vers des champs de forces polarisables haute performance - Felix Aviat, Laboratoire de chimie théorique |
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15:15 - 15:30 |
› Hydrophobic Cluster Analysis for the investigation of protein interaction sites and remote homology. - Alexis Lamiable, Institut de minéralogie, de physique des matériaux et de cosmochimie |
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15:30 - 15:45 |
› Design of stable cyclic peptides for therapeutic applications - Guillaume Postic, Institut de minéralogie, de physique des matériaux et de cosmochimie |
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15:45 - 16:15
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Coffee break |
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16:15 - 17:00
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Genomic and metagenomic sequence analysis |
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16:15 - 16:30 |
› Reconstructing ancestral genomes and retracing past chromosomal rearrangements. - Fleiss Aubin, Biologie Computationnelle et Quantitative |
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16:30 - 16:45 |
› Deep learning approaches on genomic and metagenomic sequences to create embedding and make decision. - Maxence Queyrel, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition |
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16:45 - 17:00 |
› Improving domain annotation and functional characterization with clade-specific probabilistic models - Riccardo Vicedomini, Biologie Computationnelle et Quantitative |
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